Cytotherapy. 2004; 6(6) : 596-601. Mesenchymal stem cell-based cartilage tissue engineering: cells, scaffold and biology. Song L, Baksh D, Tuan RS: Cartilage Biology and Orthopedics Branch, National Institute of Arthritis, and Musculoskeletal and Skin Diseases, Department of Health and Human Services, NIH, Bethesda, MD 20892-8022, USA. Abstract Cartilage repair and regeneration by stem cell-based tissue…

Med J Aust. 2004 Mar 1; 180(5 Suppl) : S35-8. Orthopaedic tissue engineering: from laboratory to the clinic. Oakes BW Department of Anatomy and Cell Biology, Monash University, Wellington Road, Clayton, VIC 3800, Australia. Barry.Oakes@med.monash.edu.au Abstract Tissue engineering involves the use of cells (either adult, mesenchymal or embryonic stem cells) coupled with biological or artificial…

J Musculoskelet Neuronal Interact. 2002 Jun; 2(4) : 309-20. Adult mesenchymal stem cells: potential for muscle and tendon regeneration and use in gene therapy. Pittenger M, Vanguri P, Simonetti D, Young R. Osiris Therapeutics, Inc., Baltimore, Maryland 21231, USA. mpittenger@osiristx.com Abstract The expansion potential and plasticity of stem cells, adult or embryonic, offer great promise…

Unfallchirurg. 2002 Feb; 105(2) : 88-94 Tissue engineering of tendons and ligaments. A new challenge. Bosch U, Krettek C: Abstract Injuries to ligaments and tendons heal by formation of inferior repair tissue. This may result in severe joint dysfunction. Because of an increased occurrence of sports-related injuries, musculoskeletal disorders may become one of the major…

Clin Sports Med. 2001 Apr; 20(2) : 403-16, viii. Treatment of osteochondral injuries. Genetic engineering. Martinek V, Fu FH, Lee CW, http://www.ncbi.nlm.nih.gov/pubmed?term=%22Huard%20J%22[Author] Department of Orthopaedic Surgery, University of Pittsburgh, Pennsylvania, USA. Abstract Articular cartilage injuries are commonly encountered problems in sports medicine and orthopaedics. The treatment of chondral and osteochondral lesions, which possess only a…

Tissue Eng. 2003 Aug; 9(4) : 733-44. Cell-based therapy in the repair of osteochondral defects: a novel use for adipose tissue. Nathan S, Das De S, Thambyah A, Fen C, Goh J, Lee EH Department of Orthopedics, National University Hospital, National University of Singapore, Singapore. Abstract Mesenchymal stem cells are currently procured from periosteum and…

Mol Biol Cell. 2002 Dec; 13(12) : 4279-95. Human adipose tissue is a source of multipotent stem cells. Zuk PA, Zhu M, Ashjian P, De Ugarte DA, Huang JI, Mizuno H, Alfonso ZC, Fraser JK, Benhaim P, Hedrick MH Department of Surgery and Orthopedics, Regenerative Bioengineering and Repair Laboratory, UCLA School of Medicine, Los Angeles,…

J Am Acad Orthop Surg. 2002 Jan-Feb; 10(1) : 6-15. Gene therapy and tissue engineering in orthopaedic surgery. Musgrave DS, Fu FH, Huard J Department of Orthopaedic Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, USA. Abstract A new biologic era of orthopaedic surgery has been initiated by basic scientific advances that have resulted in…

Tissue Eng. 1999 Aug; 5(4) : 327-37. Meniscus regeneration in a rabbit partial meniscectomy model. Walsh CJ, Goodman D, Caplan AI, Goldberg VM. The Departments of Biology and Orthopaedics, Case Western Reserve University and University Hospitals of Cleveland, Cleveland, Ohio 44106, USA. Abstract Meniscectomy is known to be associated with osteoarthrosis of the knee. The…