Br J Pharmacol. 2011 May;163(1):106-15. doi: 10.1111/j.1476-5381.2011.01246.x. Treatment of COPD Is a regenerative approach viable for the treatment of COPD? Hind M, Maden M. Source Royal Brompton Hospital, National Heart and Lung Institute, Imperial College, London, UK. m.hind@imperial.ac.uk Abstract Degenerative lung diseases such as chronic obstructive pulmonary disease (COPD) are common with huge worldwide morbidity.…

Cell Transplant. 2011 Mar 7. [Epub ahead of print] Mesenchymal stem cells restore lung function by recruiting resident and non-resident proteins. Jungebluth P, Luedde M, Ferrer E, Luedde T, Vucur M, Peinado VI, Go T, Schreiber C, Richthofen MV, Bader A, Haag J, Darsow KH, Bartel SJ, Lange HA, Furlani D, Steinhoff G, Macchiarini P.…

Intensive Care Med. 2011 Jun 9. [Epub ahead of print] Mechanisms of cellular therapy in respiratory diseases. Abreu SC, Antunes MA, Pelosi P, Morales MM, Rocco PR. Source Laboratório de Investigação Pulmonar, Centro de Ciências da Saúde, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Avenida Carlos Chagas Filho, s/n, Bloco…

Annu Rev Med. 2007;58:285-98. Stem cells and chronic lung disease. Gomperts BN, Strieter RM. Source Mattel Children’s Hospital, Department of Pediatrics, Division of Pediatric Hematology, Oncology, David Geffen School of Medicine at UCLA, Los Angeles, California 90095, USA. bgomperts@mednet.ucla.edu Abstract Stem cells have been shown to contribute to the repair and regeneration of injured lungs.…

urr Stem Cell Res Ther. 2007 Sep;2(3):197-208. Deriving respiratory cell types from stem cells. Olsson F, Denham M, Cole TJ, Hooper SB, Mollard R. Source Department of Physiology, Monash University, Clayton, 3800, Australia. Abstract The reported pluripotential capabilities of many human stem cell types has made them an attractive area of research, given the belief…

Ther Adv Respir Dis. 2008 Jun;2(3):173-7. Stem cell therapy: the great promise in lung disease. Siniscalco D, Sullo N, Maione S, Rossi F, D’Agostino B. Source Department of Experimental Medicine, Section of Pharmacology, Second University of Naples, via S. Maria di Costantinopoli, 16-80138 Napoli, Italy. dariosin@uab.edu Abstract Lung injuries are leading causes of morbidity and…

Panminerva Med. 2009 Mar;51(1):5-16. Mesenchymal stem cells and inflammatory lung diseases. Iyer SS, Co C, Rojas M. Source Division of Pulmonary, Allergy and Critical Care Medicine, Emory University, Atlanta, GA 30322, USA. Abstract Mesenchymal stem cells (MSCs) are emerging as a therapeutic modality in various inflammatory disease states. A number of ongoing randomized Phase I/II…

[Article in Japanese] Kubo H. Source Department of Geriatrics and Gerontology, Tohoku University Hospital. Abstract To develop a new cell based therapy for chronic obstructive pulmonary disease (COPD), we need to understand 1) the role of tissue-specific and bone marrow-derived stem cells, 2) extracellular matrix, and 3) growth factors. Recently, bronchioalveolar stem cells were identified…