Cytotherapy. 2011 Jan 13. [Epub ahead of print] Comparison of mesenchymal stem cells from adipose tissue and bone marrow for ischemic stroke therapy. Ikegame Y, Yamashita K, Hayashi SI, Mizuno H, Tawada M, You F, Yamada K, Tanaka Y, Egashira Y, Nakashima S, Yoshimura SI, Iwama T. Source Department of Neurosurgery, Gifu University Graduate School…

Cells. 2010 Jun;28(6):1099-106 A long-term follow-up study of intravenous autologous mesenchymal stem cell transplantation in patients with ischemic stroke. • Lee JS, Hong JM, Moon GJ, Lee PH, Ahn YH, Bang OY, • We previously evaluated the short-term follow-up preliminary data of mesenchymal stem cells (MSCs) transplantation in patients with ischemic stroke. The present study…

• J Transl Med. 2010;8:63 • Adipose-derived mesenchymal stem cells markedly attenuate brain infarct size and improve neurological function in rats. • Leu S, Lin YC, Yuen CM, Yen CH, Kao YH, Sun CK, Yip HK • BACKGROUND: The therapeutic effect of adipose-derived mesenchymal stem cells (ADMSCs) on brain infarction area (BIA) and neurological status…

Cochrane Database Syst Rev. 2010;9:CD007231 Stem cell transplantation for ischemic stroke. Boncoraglio GB, Bersano A, Candelise L, Reynolds BA, Parati EA BACKGROUND: Studies in animal models of ischemic stroke have shown that stem cells transplanted into the brain can lead to functional improvement. However, to date, evidence for the benefits of stem cell transplantation in…

J Neurol Sci. 2010 Sep 21; Enhancing trophic support of mesenchymal stem cells by ex vivo treatment with trophic factors. Choi YJ, Li WY, Moon GJ, Lee PH, Ahn YH, Lee G, Bang OY BACKGROUND: Several studies have examined the enhanced efficacy of mesenchymal stem cells (MSCs) using neurotrophic factor transfection in ischemic rat models.…

J Clin Invest. 2010 Jan 4;120(1):29-40 Stem cells in human neurodegenerative disorders–time for clinical translation? Lindvall O, Kokaia Z Stem cell-based approaches have received much hype as potential treatments for neurodegenerative disorders. Indeed, transplantation of stem cells or their derivatives in animal models of neurodegenerative diseases can improve function by replacing the lost neurons and…

Discov Med. 2010 Mar;9(46):236-42. The potential of mesenchymal stem cells for neural repair. Miller RH, Bai L, Lennon DP, Caplan AI. Source Centers for Stem Cells and Regenerative Medicine, Translational Neuroscience, Department of Neurosciences, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA. rhm3@case.edu Abstract Developing effective therapies for serious neurological insults remains…

Brain Res. 2010 Jun 2;1334:65-72. Epub 2010 Mar 28. Human mesenchymal stem cell transplantation protects against cerebral ischemic injury and upregulates interleukin-10 expression in Macacafascicularis. Li J, Zhu H, Liu Y, Li Q, Lu S, Feng M, Xu Y, Huang L, Ma C, An Y, Zhao RC, Wang R, Qin C. Source Institute of Laboratory…

Adv Exp Med Biol. 2010;671:41-57. Stem cell transplantation methods. Tran KD, Ho A, Jandial R. Source UCSD School of Medicine, San Diego, California, USA. Abstract Just a few short years ago, we still used to think that we were born with a finite number of irreplaceable neurons. However, in recent years, there has been increasingly…

Adv Exp Med Biol. 2010;671:105-16. Stem cells in the treatment of stroke. Urbaniak Hunter K, Yarbrough C, Ciacci J. Source University of Michigan, Department of Radiation Oncology, UH B2C490, 1500 E. Medical Center Dr., Ann Arbor, Michigan, USA. kurbania@med.umich.edu Abstract Stroke is an often devastating insult resulting in neurological deficit lasting greater than 24 hours.…