by Mrudula M Mohanan, Radhakrishna Shetty, Claus Heiner Bang-Berthelsen, Kiran Kumar Mudnakudu-Nagaraju Published – August 2023 Role of mesenchymal stem cells and short chain fatty acids in allergy Abstract Allergic diseases are broadly classified as IgE-mediated type-I hypersensitivity immune reactions due to exposure to typically harmless substances known as allergens. These allergenic substances activate antigen…

by Barbara Lukomska, Luiza Stanaszek, Ewa Zuba-Surma, Pawel Legosz, Sylwia Sarzynska, and Katarzyna Drela Published – April 2019 Challenges and Controversies in Human Mesenchymal Stem Cell Therapy Abstract Stem cell therapy is being intensely investigated within the last years. Expectations are high regarding mesenchymal stem cell (MSC) treatment in translational medicine. However, many aspects concerning…

by Anup Kumar Ghosh, Aparajita Ghosh, Prasanta Kumar Das Published – January 2024 Nanotechnology Meets Stem Cell Therapy for Treating Glioblastomas: A Review Abstract Malignant glioblastoma, also known as Glioblastoma multiforme (GBM), is one of the most aggressive subtypes, characterized by wide vascularization and complex invasion. The currently available standard care for GBM includes maximal…

by Vija L, Farge D, Gautier JF, Vexiau P, Dumitrache C, Bourgarit A, Verrecchia F, Larghero J. Published – February 2009 Mesenchymal stem cells: Stem cell therapy perspectives for type 1 diabetes Abstract Mesenchymal stem cells (MSCs) are multipotent non-haematopoietic progenitor cells that are being explored as a promising new treatment for tissue regeneration. Although…

by Meenakshi Gaur, Marek Dobke and Victoria V. Lunyak Published – January 2017 Mesenchymal Stem Cells from Adipose Tissue in Clinical Applications for Dermatological Indications and Skin Aging Abstract Operating at multiple levels of control, mesenchymal stem cells from adipose tissue (ADSCs) communicate with organ systems to adjust immune response, provide signals for differentiation, migration,…

Yang Song, Hui Du, Chengxiang Dai, Li Zhang, Suke Li, David J Hunter, Liangjing Lu, Chunde Bao Human adipose-derived mesenchymal stem cells for osteoarthritis: a pilot study with long-term follow-up and repeated injections Abstract Aim: This study aimed to evaluate the safety and therapeutic potential of autologous human adipose-derived mesenchymal stem cells (haMSCs) in patients…

by Tracy S. P. Heng, Jarrod A. Dudakov, Danika M. P. Khong, Ann P. Chidgey & Richard L. Boyd Published – October 2009 Stem cells – meet immunity Abstract The ability of stem cells to differentiate into various different cell types holds great promise for the treatment of irreversible tissue damage that occurs in many…

Na Li & Jinlian Hua Published – February 2017 Interactions between mesenchymal stem cells and the immune system Abstract In addition to being multi-potent, mesenchymal stem cells (MSCs) possess immunomodulatory functions that have been investigated as potential treatments in various immune disorders. MSCs can robustly interact with cells of the innate and adaptive immune systems,…

Mohamad R. Issa, Ahmad S. Naja, Nour Z. Bouji and Bernard H. Sagherian Published – November 2022 The role of adipose-derived mesenchymal stem cells in knee osteoarthritis: a meta-analysis of randomized controlled trials Abstract Background: Adipose-derived mesenchymal stem cells (ADMSCs) have recently been studied for the treatment of knee osteoarthritis. The goal is pain reduction…

Yu-Xin Liu, Jia-Ming Sun, Chia-Kang Ho, Ya Gao, Dong-Sheng Wen, Yang-Dan Liu, Lu Huang, Yi-Fan Zhang Published – May 2023 Advancements in adipose-derived stem cell therapy for skin fibrosis Abstract Pathological scarring and scleroderma, which are the most common conditions of skin fibrosis, pathologically manifest as fibroblast proliferation and extracellular matrix (ECM) hyperplasia. Fibroblast proliferation…