Mol Biol Rep 2019 Oct;46(5):5257-5272. Epub 2019 Jul 20. Human intracerebroventricular (ICV) injection of autologous, non-engineered, adipose-derived stromal vascular fraction (ADSVF) for neurodegenerative disorders: results of a 3-year phase 1 study of 113 injections in 31 patients Christopher Duma 1, Oleg Kopyov 2, Alex Kopyov 2, Mark Berman 3, Elliot Lander 3, Michael Elam 3, Michael Arata 3, David Weiland 4, Ruslana Cannell 5, Chad Caraway 5, Sean Berman 3, Kristin Scord 2, Lian Stemler 2, Karlyssa Chung 2, Samuel Khoudari 2, Rory McRory 2, Chace Duma 2, Sawyer…

Cell Transplant. 2010 Aug 18; Therapeutic Effects of Umbilical Cord Blood-Derived Mesenchymal Stem Cell Transplantation in Experimental Lupus Nephritis. Authors: Chang JW, Hung SP, Wu HH, Wu WM, Yang AH, Tsai HL, Yang LY, Lee OK Msenchymal stem cells (MSCs) have been shown to possess immuno-modulatory properties. Systemic lupus erythematosus is an autoimmune disease which…

Rev Med Interne. 2009 Mar;30(3):287-99. Epub 2008 Oct 17. Mesenchymal stem cells and immunomodulation: toward new immunosuppressive strategies for the treatment of autoimmune diseases? [Article in French] Larghero J, Vija L, Lecourt S, Michel L, Verrecchia F, Farge D. Source Unité de thérapie cellulaire, Hôpital Saint-Louis, AP-HP, Paris, France. Abstract Mesenchymal stem cells (MSC) represent…

Nat Clin Pract Rheumatol. 2008 Apr;4(4):184-91 Technology Insight: hematopoietic stem cell transplantation for systemic rheumatic disease. Authors: Nikolov NP, Pavletic SZ Hematopoietic stem cells (HSCs) have the capacity for self-renewal and the potential to differentiate into all types of hematopoietic and immune system cells. These features have been successfully used to treat a multitude of…

Haematologica. 2010 Feb;95(2):284-92 Autologous hematopoietic stem cell transplantation for autoimmune diseases: an observational study on 12 years’ experience from the European Group for Blood and Marrow Transplantation Working Party on Autoimmune Diseases. Authors: Farge D, Labopin M, Tyndall A, Fassas A, Mancardi GL, Van Laar J, Ouyang J, Kozak T, Moore J, Kötter I, Chesnel…

Braz J Med Biol Res. 2007 Dec;40(12):1579-97 The use of stem cells for the treatment of autoimmune diseases. Authors: Rosa SB, Voltarelli JC, Chies JA, Pranke P Autoimmune diseases constitute a heterogeneous group of conditions commonly treated with anti-inflammatory, immunosuppressant and immunomodulating drugs, with satisfactory results in most cases. Nevertheless, some patients become resistant to…

Hematology. 2007 Jun;12(3):179-91 Haemopoietic stem cell transplantation–an evolving treatment for severe autoimmune and inflammatory diseases in rheumatology, neurology and gastroenterology. Authors: Kapoor S, Wilson AG, Sharrack B, Lobo A, Akil M, Sun L, Dalley CD, Snowden JA The concept of haemopoietic stem cell transplantation (HSCT) to treat severe autoimmune diseases has been around for several…

Arthritis Res Ther. 2007;9(2):206 Cell therapy for autoimmune diseases. Authors: Dazzi F, van Laar JM, Cope A, Tyndall A Cell therapy, pioneered for the treatment of malignancies in the form of bone marrow transplantation, has subsequently been tested and successfully employed in autoimmune diseases. Autologous haemopoietic stem cell transplantation (HSCT) has become a curative option…

Bone Marrow Transplant. 2007 Mar;39(6):317-29 ReMobilization, harvesting and selection of peripheral blood stem cells in patients with autoimmune diseases undergoing autologous hematopoietic stem cell transplantation. Authors: Statkute L, Verda L, Oyama Y, Traynor A, Villa M, Shook T, Clifton R, Jovanovic B, Satkus J, Loh Y, Quigley K, Yaung K, Gonda E, Krosnjar N, Spahovic…