Nikhil Agarwal, Christopher Mak, Christine Bojanic, Kendrick To, Wasim Khan Published online – June 2021 Meta-Analysis of Adipose Tissue Derived Cell-Based Therapy for the Treatment of Knee Osteoarthritis Abstract Osteoarthritis (OA) is a degenerative disorder associated with cartilage loss and is a leading cause of disability around the world. In old age, the capacity of…

Yu-Xin Liu, Jia-Ming Sun, Chia-Kang Ho, Ya Gao, Dong-Sheng Wen, Yang-Dan Liu, Lu Huang, Yi-Fan Zhang Published – May 2023 Advancements in adipose-derived stem cell therapy for skin fibrosis Abstract Pathological scarring and scleroderma, which are the most common conditions of skin fibrosis, pathologically manifest as fibroblast proliferation and extracellular matrix (ECM) hyperplasia. Fibroblast proliferation…

by Rasa Islam,Aleta Pupovac, Vera Evtimov, Nicholas Boyd, Runzhe Shu, Richard Boyd and Alan Trounson Published – April 2021 Enhancing a Natural Killer: Modification of NK Cells for Cancer Immunotherapy Abstract Natural killer (NK) cells are potent innate immune system effector lymphocytes armed with multiple mechanisms for killing cancer cells. Given the dynamic roles of…

Guanwen Gao, Chenyang Fan, Weiquan Li, Runzhang Liang, Chuzhong Wei, Xiaojie Chen, Yue Yang, Yueyuan Zhong, Yingqi Shao, Yi Kong, Zesong Li, and Xiao Zhu Published online – July 2021 Mesenchymal Stem Cells: Ideal seeds for treating diseases Abstract Mesenchymal stem cells (MSCs), a kind of multipotent stem cells with self-renewal ability and multi-differentiation ability,…

by Xianmei Zhong, Jie Chen, Bo Wen, Xu Wu, Mingxing Li, Fukuan Du, Yu Chen, Shuai Deng, Yueshui Zhao, Jing Shen & Zhangang Xiao Published – September 2023 Potential role of mesenchymal stem cells in T cell aging Abstract Immunosenescence occurs with progressive age. T cell aging is manifested by immunodeficiency and inflammation. The main…

by Xu-Feng Mao, Xi-Qian Zhang, Zhe-Yu Yao, Hai-Jiao Mao Published – January 2024 Advances in mesenchymal stem cells therapy for tendinopathies Abstract Tendinopathies are chronic diseases of an unknown etiology and associated with inflammation. Mesenchymal stem cells (MSCs) have emerged as a viable therapeutic option to combat the pathological progression of tendinopathies, not only because…

by Mrudula M Mohanan, Radhakrishna Shetty, Claus Heiner Bang-Berthelsen, Kiran Kumar Mudnakudu-Nagaraju Published – August 2023 Role of mesenchymal stem cells and short chain fatty acids in allergy Abstract Allergic diseases are broadly classified as IgE-mediated type-I hypersensitivity immune reactions due to exposure to typically harmless substances known as allergens. These allergenic substances activate antigen…

by Barbara Lukomska, Luiza Stanaszek, Ewa Zuba-Surma, Pawel Legosz, Sylwia Sarzynska, and Katarzyna Drela Published – April 2019 Challenges and Controversies in Human Mesenchymal Stem Cell Therapy Abstract Stem cell therapy is being intensely investigated within the last years. Expectations are high regarding mesenchymal stem cell (MSC) treatment in translational medicine. However, many aspects concerning…

by Anup Kumar Ghosh, Aparajita Ghosh, Prasanta Kumar Das Published – January 2024 Nanotechnology Meets Stem Cell Therapy for Treating Glioblastomas: A Review Abstract Malignant glioblastoma, also known as Glioblastoma multiforme (GBM), is one of the most aggressive subtypes, characterized by wide vascularization and complex invasion. The currently available standard care for GBM includes maximal…

by Vija L, Farge D, Gautier JF, Vexiau P, Dumitrache C, Bourgarit A, Verrecchia F, Larghero J. Published – February 2009 Mesenchymal stem cells: Stem cell therapy perspectives for type 1 diabetes Abstract Mesenchymal stem cells (MSCs) are multipotent non-haematopoietic progenitor cells that are being explored as a promising new treatment for tissue regeneration. Although…