Ruijiao Tian, Shibo Su, Yang Yu, Siqiang Liang, Chuqing Ma, Yang Jiao,Weihong Xing, Ziheng Tian, Tongmeng Jiang, Juan Wang Published – April 2024 Revolutionizing osteoarthritis treatment: How mesenchymal stem cells hold the key Abstract Osteoarthritis (OA) is a multifaceted disease characterized by imbalances in extracellular matrix metabolism, chondrocyte and synoviocyte senescence, as well as inflammatory…

Yang Song, Hui Du, Chengxiang Dai, Li Zhang, Suke Li, David J Hunter, Liangjing Lu, Chunde Bao Human adipose-derived mesenchymal stem cells for osteoarthritis: a pilot study with long-term follow-up and repeated injections Abstract Aim: This study aimed to evaluate the safety and therapeutic potential of autologous human adipose-derived mesenchymal stem cells (haMSCs) in patients…

by Rui-Cheng Zhang, Wen-Qi Du, Jing-Yuan Zhang, Shao-Xia Yu, Fang-Zhi Lu, Hong-Mei Ding, Yan-Bo Cheng, Chao Ren, De-Qin Geng Published – March 2021 Mesenchymal Stem Cell Treatment for Peripheral Nerve Injury: A Narrative Review Abstract Peripheral nerve injuries occur as the result of sudden trauma and lead to reduced quality of life. The peripheral nervous…

by Portland Press Ltd Published – August 2021 Stem cells and regenerative medicine in sport science The estimated cost of acute injuries in college-level sport in the USA is ∼1.5 billion dollars per year, without taking into account the cost of follow up rehabilitation. In addition to this huge financial burden, without appropriate diagnosis and…

by Maura Faraci, Gianluca Dell’Orso, Stefano Giardino, Filomena Pierri Published – May 2022 Autoimmune diseases after allogeneic stem cell transplantation: a clinician’s guide and future outlook Abstract Introduction: Autoimmune disease (AD) may occur after allogeneic hematopoietic stem cell transplantation (HSCT). The autoimmune mechanism seems to be related to an imbalance of the immune regulation effect…

by Basem Ali Zogel, Hussam Masoud Darraj, Zenat Ahmed Khired, Fahad Yahya AlArishi Published – July 2023 Utilizing mesenchymal stem cells to improve the healing process of the medial collateral ligament in the knee Abstract The healing process of the medial collateral ligament (MCL) in the knee is often slow, resulting in adverse outcomes such…

by Xianmei Zhong, Jie Chen, Bo Wen, Xu Wu, Mingxing Li, Fukuan Du, Yu Chen, Shuai Deng, Yueshui Zhao, Jing Shen & Zhangang Xiao Published – September 2023 Potential role of mesenchymal stem cells in T cell aging Abstract Immunosenescence occurs with progressive age. T cell aging is manifested by immunodeficiency and inflammation. The main…

by Xu-Feng Mao, Xi-Qian Zhang, Zhe-Yu Yao, Hai-Jiao Mao Published – January 2024 Advances in mesenchymal stem cells therapy for tendinopathies Abstract Tendinopathies are chronic diseases of an unknown etiology and associated with inflammation. Mesenchymal stem cells (MSCs) have emerged as a viable therapeutic option to combat the pathological progression of tendinopathies, not only because…

by Mrudula M Mohanan, Radhakrishna Shetty, Claus Heiner Bang-Berthelsen, Kiran Kumar Mudnakudu-Nagaraju Published – August 2023 Role of mesenchymal stem cells and short chain fatty acids in allergy: A prophylactic therapy for future Abstract Allergic diseases are broadly classified as IgE-mediated type-I hypersensitivity immune reactions due to exposure to typically harmless substances known as allergens.…

by by Meenakshi Gaur, Marek Dobke and Victoria V. Lunyak Published – January 2017 Mesenchymal Stem Cells from Adipose Tissue in Clinical Applications for Dermatological Indications and Skin Aging Abstract Operating at multiple levels of control, mesenchymal stem cells from adipose tissue (ADSCs) communicate with organ systems to adjust immune response, provide signals for differentiation,…